KLF2 and cancer: Krüppel-like factor 2 (KLF2), is described as a mechanosensitive transcription factor (Niu et al. 2019; Dabravolski et al. 2022), hence can be activated by physical triggers, and was recently shown to inhibit cell migration in various forms of cancers (Wang et al. 2019; Lin et al. 2019).