RAC1 and nervous system disorder: Rac1, a Rho GTPase, is a critical regulator of actin signaling cascades (Bosco et al., 2009; Yasuda, 2017), and human mutations in Rac1 are associated with neurological disorders (Bai et al., 2015; Reijnders et al., 2017; Zamboni et al., 2018).