MYCN and cancer: Altogether, overexpression of MYC – or of its paralogues, MYCN or MYCL – is a widespread event in most cancer types [7, 8, 9, 10, 11, 12, 13], and contributes to multiple hallmarks of the transformed phenotype [14, 15], including cell‐intrinsic and systemic features, such as angiogenesis, modulation of the tumor microenvironment, or immune evasion [13, 16].