Adjuvants for a dry eye treatment that have been proposed Topical treatment with alpha-linolenic acid significantly reduced corneal fluorescein staining in dry eye-induced animals compared to vehicle and untreated controls, decreased CD11b(+) cell number, corneal IL-1 and TNF- Expression, and conjunctival TNF- Expression. Here, IL1B is linked to Keratoconjunctivitis sicca.