Following anti-VEGF treatment, the decrease in CMT (ΔCMT) for patients with HF in the nAMD and PCV groups, 72.00 (28.00–136.00) and 82.50 μm (25.00–175.00) respectively, was greater than for those without HF (P = 0.001 and P = 0.057 respectively). The gene discussed is VEGFA; the disease is hydrops fetalis.