Similarly, the top 20 GO and signaling pathway enrichment analyses were shown in Figures 5(a) and 5(b), including GO entries for apoptosis, growth factor stimulation response and cellular response to chemical stress and reactive oxygen metabolic processes, and signaling pathways such as cancer-related signaling pathway, FOXO signaling pathway, AGE-RAGE signaling pathway in diabetic complications, interleukin signaling pathway, and PI3K-AKT signaling pathway, which were considered to be the most important biological processes and signaling pathways involved in FG against AIC. Here, RENBP is linked to cancer.