Furthermore, the mutation (2607583 A/G) was noticed to be associated with SCS, while the SNPs at position 2484891 C/T, and 2525852 T/G were linked to IL-6 and IFN-γ, respectively, however no correlation of 2607583 A/G in TRAPPC9 gene was found with SCC, SCS and serum cytokines (IL-6 and IFN-γ) (36). This evidence concerns the gene TRAPPC9 and Saethre-Chotzen syndrome.