The commonly involved pathways are including TGF-beta signaling pathway, Tuberculosis, Chagas disease (American trypanosomiasis), Leishmaniasis, Pertussis, Viral carcinogenesis, Herpes simplex infection, Staphylococcus aureus infection, Legionellosis, Chemokine signaling pathway, PPAR signaling pathway, Vascular smooth muscle contraction, Toxoplasmosis, Influenza A,Viral myocarditis and Signaling pathways regulating pluripotency of stem cells. This evidence concerns the gene PPARA and pertussis.