Analysis of the interaction of P5 and P20 with culture at the control temperature (37°C) identified pathways associated with EGFR tyrosine kinase inhibitor resistance, viral myocarditis, PI3K-Akt signaling, focal adhesion, PPAR signaling, signaling pathways regulating the pluripotency of stem cells, mTOR signaling, leukocyte transendothelial migration, Wnt signaling, and tight junction. Here, PPARA is linked to viral myocarditis.