Further studies showed the basal expression of NRF2 was higher in androgen-resistant PCa cells (DU-145 and PC3) as compared to androgen sensitive PCa cells (LNCaP), and finasteride treatment selectively increased NRF2 expression in DU-145 and PC-3 cells, but not in LNCaP cells. This evidence concerns the gene NFE2L2 and posterior cortical atrophy.