NFE2L2 and posterior cortical atrophy: We have reported that manganese porphyrins protect normal prostate cells from radiation-induced fibrosis by enhancing NRF2 activity, while inhibiting PCa growth after radiation (Tong et al., 2016; Chatterjee et al., 2017; Shrishrimal et al., 2017; Chatterjee et al., 2018; Chatterjee et al., 2020; Shrishrimal et al., 2020; Zhu et al., 2020).