INS and type 2 diabetes mellitus: The pooled prevalence of EPI was 27% (95% CI: 17%–37%, I2 = 90.95%) in type 2 diabetes patients with higher insulin requirement group (1 group), while patients with lower insulin requirement group (2 group) had a lower incidence of EPI (15%, 95% CI: 1%–40%, I2 = 95.17%) (Supplementary Figure 1).