EGFR and biliary tract cancer: Figure 2B shows common genetic alterations of the hepatobiliary samples profiled as part of clinical validation. This figure shows that the HCC samples harbored increased common alterations in hepatobiliary cancers compared to cancers of the biliary tract. Figure 2C shows genetic alterations from lung samples showing EGFR exon 18−20 hotspots and exon 19 frameshift deletions.