PARD3 contains multiple postsynaptic densities and is localized to tight junctions; in addition, it is correlated with invasion in lung squamous cell carcinoma via impaired STAT3 signaling (Ohno, 2001; Ozdamar et al., 2005; Bonastre et al., 2015). The gene discussed is PARD3; the disease is squamous cell lung carcinoma.