NDRG1 and Familial prostate cancer: A truncated isoform of NDRG1 has been observed in prostate cancer cell lines but not normal cell lines, this could explain the contradictory roles observed in cells, the full length isoform may be responsible for the tumour suppressor roles of NDRG1 and the truncated version for the oncogenic roles, this warrants further investigation (Park et al., 2018).