This component can significantly reduce the level of serum IgA in rats with IgA nephropathy and improve the degree of abnormal glycosylation, as well as downregulate the level of the CD71 molecule, the main receptor of IgA1 in the glomerular thylakoid region, and reduce the deposition of IgA1 in the thylakoid region, thus inhibiting the proliferation of glomerular thylakoid cells and the increase of stroma [40]; (2) protection of podocytes: raffinose polysaccharide can stabilize the podocyte skeleton, reduce the damage to the podocytes, and protect the podocytes. Here, TFRC is linked to IgA glomerulonephritis.