A significant reduction was found in the SOD levels of brain tissue homogenates after 21 days of experimentally induced parkinsonism with haloperidol (P < 0.001), but groups treated with PAME of 800 mg/kg had significantly enhanced the level of SOD after 21 days (P < 0.001) (Table 4). The gene discussed is SOD1; the disease is Parkinsonism.