On this basis, the cardiac protection mechanism of WenXin KeLi improving CX43 expression and reducing the risk of arrhythmia after MI was further analyzed from the perspective of the PI3K-AKT-mTOR autophagy pathway, hoping to provide new experimental evidence for revealing the molecular mechanism of TCM in the prevention and treatment of arrhythmia after MI. Here, AKT1 is linked to Arrhythmia.