It revealed that the cardioprotective mechanism of WenXin KeLi in improving cardiac structure and function and reduced the risk of arrhythmia in rats after MI, which was related to the activation of the PI3K- AKT-mTOR signal pathway and the improvement of cardiac autophagy and CX43 expression in rats after MI (Figure 6). Here, GJA1 is linked to Arrhythmia.