In this study, the correlation analysis between autophagy and VFT after MI showed that there was a significant negative correlation between cardiomyocyte autophagy-related proteins Beclin1, LC3II/LC3I, and VFT, and a significant positive correlation between P62 expression and VFT, suggesting that the overactivation of myocardial autophagy after MI was related to the increased risk of arrhythmia. This evidence concerns the gene SQSTM1 and myocardial infarction.