These were ARRB2, BIRC3, CD14, DYNLL1, FCER1G, FCGR1A, FCGR2B, FGR, HCK, and PRKCD. As these genes are closely linked and are at the hub of the PPI network, they are expected to become targets for periodontitis treatment. The gene discussed is PRKCD; the disease is periodontitis.