Inactivation of ALKBH5 causes an increase in m6A levels on mRNAs, and studies have shown that ALKBH5 is essential for the progression of non-neoplastic and neoplastic diseases of the reproductive, immune, circulatory, and nervous systems (Zheng et al., 2013; Cheng et al., 2021; Dong et al., 2021). Here, ALKBH5 is linked to neoplasm.