ZEB1 and neoplasm: For instance, the analysis demonstrated that up-regulated ZEB1-AS1 expression was associated with increased drug sensitivity of tumor cells to nelarabine, palbociclib, fluphenazine, asparaginase, LEE-011, ifosfamide, hydroxyurea and dexrazoxane, while increased ZEB1-AS1 expression was related to the increased resistance to vemurafenib in COAD patients (Figure 8B).