In breast cancer patient datasets, AQP9 expression significantly correlated with specific markers, including eCD86 and CD115 (monocytes); CD68, IL10, and CCL-2 (TAMs); IRF5 and PTGS2 (M1 macrophages); and CD163, MS4A4A, and VSIG4 (M2 macrophages) (104). This evidence concerns the gene AQP9 and breast cancer.