ssGSEA analysis showed that SEMA4F was negatively correlated with tumor inflammation signature, ECM-related gene, angiogenesis, apoptosis, inflammatory response, P53 pathway, IL-10 anti-inflammatory signaling pathway, genes up-regulated by reactive oxygen species (ROS), tumor proliferation signature, DNA Repair, G2M checkpoint, MYC targets, TGFB, and DNA replication (Figure S4C). The gene discussed is TP53; the disease is neoplasm.