MUC16 and neoplasm: Particularly, advanced HGSOC patients with age at diagnosis ≤60 years or serum CA125 ≤401 U/ml showed a median PFS of 48 months versus 24 months of women with tumor diagnosed over 60 years of age (95% CI, 34–57 vs. 15–29; log-rank p-value=0.0002) or serum CA125 >401 U/ml (95% CI, 29–57 vs. 15–34; log-rank p-value=0.002).