HAVCR2 and T-cell non-Hodgkin lymphoma: The results showed that 2 cases (Case1 and 2) existed in the mutations in TIM-3 gene on 25 cases with T-cell lymphoma; the incidence of TIM-3 mutations was 8.0%(2/25).Compared with healthy individuals(n=87),Y82C heterozygote in T-cell lymphoma was significantly enrichment.