In addition, according to the analysis of the TCGA database, the research group also found that the expression of GATA6 was decreased in stage IV CRC, while the expression of MIR100HG was increased, and the increase in the expression of miR-125b could enhance the inhibitory effect of GATA6, which in turn promoted the increased expression of MIR100HG. The gene discussed is GATA6; the disease is colorectal carcinoma.