Seeing that the CHD1 cistrome overlaps with the cistromes of several transcription factors implicated in driving disease progression, it would be curious to understand the nature of the interactions between CHD1 and these transcription factors, and how CHD1 cooperates with these transcription factors to regulate the AR cistrome in the normal prostate and during prostate cancer onset. This evidence concerns the gene CHD1 and Familial prostate cancer.