Moreover, AtMYB15 and OsMYB30 were reported to regulate PAL, C4H, 4CL, HCT, C3H, COMT, and CAD to enhance lignin accumulation and defense against Pst DC3000 (AvrRpm1) and BPH, respectively (He et al., 2020; Kim et al., 2020). The gene discussed is CAD; the disease is benign prostatic hyperplasia.