LTF and acute myeloid leukemia: Back in 1988, Davey et al. reported a quantitative decrease in LTF staining in AML and myelodysplasia, which supports the concept that abnormal neutrophils and bands are derived from a malignant clone of myeloid precursor cells [62] and also is consistent with our expectations for LTF to be a candidate biomarker for AML prognosis.