In this process, CAFs can recruit immunosuppressive cells, including myeloid-derived suppressor cells (MDSCs) and, through the induction of cytokines such as IL-6 and IL-11, and participate in tumor immune evasion mechanisms (Tang et al., 2012; Mace et al., 2013; Pothula et al., 2020). Here, IL6 is linked to neoplasm.