To discover the relationship between risk scores and tumor-infiltration immune cells, we applied seven approaches for evaluating tumor-infiltration immunity cells as well as showed that B cell memory, cancer-related fibroblast, class-changed memory B cell, macrophage M0, macrophage M1, NK cell activation, T cell CD4+ central memory, T cell CD4+ memory activation T cell regulatory (Tregs), and T cell CD8+ central memory was positively associated with risk scores. The gene discussed is CD4; the disease is cancer.