The postoperative plasma concentration of CRP was associated with the incidence of postoperative delirium before and after adjusting for age, sex, preoperative MMSE, and day of postoperative CRP measurement (adjusted OR per one standard deviation change in CRP: 1.51; 95% CI: 1.05–2.16; P = 0.026; Table 2). The gene discussed is CRP; the disease is delirium.