This is demonstrated in Figure 2, in which participants with 10th (9.23 mmol/L), 25th (10.81 mmol/L), or 50th percentile (13.16 mmol/L) of preoperative homocysteine plasma concentration demonstrated a stronger association between the postoperative plasma concentration of CRP and the postoperative delirium incidence when compared with participants in the 75th percentile (18.79 mmol/L). The gene discussed is CRP; the disease is delirium.