ROC curves were performed, and the results indicated that eotaxin, G-CSF, IFN-α, IL-17A, IL-6, and MCP-1, and RANTES exhibited potential values in predicting the postoperative recurrence of CRSwNP, and eotaxin, IL-17A, and RANTES showed stronger predictive ability than other indicators (AUC > 7.0, P < 0.05) (Figure 2). This evidence concerns the gene CCL5 and chronic rhinosinusitis with nasal polyps.