This work team with the corresponding author named Didier Payen found that taking advantage of interleukin (IL)-7, an immune-mediated modulator in anti-programmed cell death, might be the future in the treatment of sepsis, evidenced by the suppression of cytokine as well as the exhaustion of T cell (Hotchkiss et al., 2013b). The gene discussed is IL7; the disease is Sepsis.