BDNF and memory impairment: Lin et al. stimulated “Shenting” (DU24) and “Baihui” (DU20) by EA, and showed improvements in memory impairment in rats with cerebral ischemia-reperfusion (I/R) injury, along with upregulation of the expression levels of BDNF and PSD-95; thus, the mechanism of action underlying the effects of EA is related to the improvement of BDNF-mediated synaptic plasticity in hippocampal neurons [56].