Tumor tissues from patients with high-risk scores tended to express high levels of risk mRNAs (POSTN, EFNB2, GOLM1, and HMMR), whereas tumor tissues from patients with low-risk scores tended to express high levels of protective mRNAs (TPSB2 and CBFA2T3) (Figure S1A, D). The gene discussed is POSTN; the disease is neoplasm.