Henningsen et al. (30) did not find significant differences in either the genotypic or allelic frequency of IL-10-1082 between patients with AF and the control group, although the expression of inflammation and cell adhesion molecules in a rat model of venous thrombosis was inhibited by viral IL-10 gene transfer (40), and the IL-10-1082A/G polymorphism is associated with the risk of deep venous thrombosis (41). The gene discussed is IL10; the disease is atrial fibrillation.