Compared with those in the control group, the levels of IL-4 in patients with AF-related venous thrombosis, arterial thrombosis, or major bleeding events increased by 53- (0.53 vs. 0.01 pg/ml), 17- (0.17 vs. 0.01 pg/ml) and 19-fold (0.19 vs. 0.01 pg/ml), respectively. The gene discussed is IL4; the disease is Arterial thrombosis.