IL17A and atherosclerosis: Similar to a recent study, Zhang et al. (19) reported recently that IL-17A could bind to IL-17RA on the endothelial cell membrane and promote endothelial cell senescence, which is one of the main causes of structural changes and blood vessel dysfunction and the basis of atherosclerosis (20), by activating the nuclear factor kappa B (NF-κB)–p53–Rb signaling pathway.