NFKB1 and diabetes mellitus: In 2012, Toshihiro Miura et al. reported that Lagerstroemia speciosa L., a rich source of corosolic acid as well as ellagitannins, was responsible for blocking the activation of NF-κB in a dose- and time-dependent manner in H9c2 cell line, which modulated anti-inflammatory action resulting in inhibition of diabetes-induced cardiomyocyte hypertrophy (147, 148).