For example, probiotics and prebiotics (Lactobacillus casei, Bifidobacterium lactis, Lactobacillus plantarum, Lactobacillus rhamnosus, oligosaccharides, inulin) have shown a reduction in inflammatory cytokines (TNF-α and IL-17a) in patients with PCOS as reported by Gamze Yurtdaş et al. (111, 170). The gene discussed is TNF; the disease is polycystic ovary syndrome.