The Boxplot analysis revealed that LCN2 CG probesets of the promoter region were methylated (median beta value ≥0.6) or partial methylated (0.6 < median beta value <0.2) in most TCGA tumor types, including the cg13518265 probeset that was highly methylated in 30 tumor types. The gene discussed is LCN2; the disease is neoplasm.