These results were consistent with previous findings indicating a positive correlation between gene expression and intragenic DNA methylation of some genes dysregulated in melanoma, including MMP9 (Candido et al., 2019), whose overexpression was significantly correlated with hypermethylation of the intragenic region (Falzone et al., 2016a; Klassen et al., 2018). The gene discussed is MMP9; the disease is melanoma.