IGHE and asthma: However, we did not find studies which have evaluated the usefulness of the measurement of cumulative IgE specific for respiratory allergens (e.g., by PhadiatopTM) for a group of patients with severe asthma aiming at the determination of asthma phenotypes and for the assessment if cumulative IgE levels specific for respiratory allergens could be a biomarker predicting the success of anti-IgE therapy.