Of these patients, three had SCID (1 Artemis, 2-RAG1), four had CVID, three had AIRE, one had DOCK8 deficiency, one had IPEX syndrome, one had CGD, one had STAT1, and one had PIK3CD. This evidence concerns the gene RAG1 and immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome.