The intraperitoneal injection of the IFN-γ and poly(I:C)-primed MSCs into the mice with colitis illustrated alleviated pathological condition of colon by decreasing the infiltration of immune cells into and the expression of pro-inflammatory cytokines in colon tissue, spleen and mesenteric lymph nodes and by promoting epithelial regeneration, enterocyte proliferation and Treg expansion (111). Here, IFNG is linked to colitis.