TIGIT expression showed a positive correlation with the infiltration scores of CD8 T cells (especially in SKCM), M1 macrophages in 12 kinds of cancers, naive B cells in 10 kinds of cancers, activated memory CD4 T cells, Tregs in LUAD, LUSC, LIHC, SKCM, THCA, COADREAD and activated NK cells in LUAD, LUSC, SKCM, STES, BLCA. Here, CD4 is linked to cancer.