DSG3 and acquired polycythemia vera: We observed eight permutations of contradictions to the DCH within PV patients: i) mucocutaneous PV in the presence of the following antibody patterns: a) anti-Dsg3+/1-, b) anti-Dsg3-/1+, and c) anti-Dsg3-/1-, ii) mucosal only PV carrying a) anti-Dsg3-/1-, b) anti-Dsg3-/1+, or c) anti-Dsg3+/1+, iii) cutaneous only PV (with any autoantibody pattern), and iv) a PF phenotype in the absence of anti-Dsg3 and -1 (Figure 1).