We examined all active PV subjects according to their ethnicity, regardless of whether they contradict or conform to the DCH, and classified their autoantibody profile from each visit’s blood draw into one of four subgroups; i) anti-Dsg1+/3+, ii) anti-Dsg1-/3+, iii) anti-Dsg1+/3-, and iv) anti-Dsg1-/3-, using the 20 IU/mL cutoff for anti-Dsg1/3 positivity. Here, DSG1 is linked to acquired polycythemia vera.