In late DN, scores for CD8 T cell, MNP, Peritubular capillary endothelium, Plasmacytoid dendritic cell, Epithelial, Principal, and Fibroblast were significantly higher than in the other two groups, whereas scores for Proximal tubule, Connecting tubule, Glomerular endothelium, and Podocyte were significantly lower. The gene discussed is CD8A; the disease is liver dysplastic nodule.