CD8A and cancer: Firstly, in the Cancer Immunity Cycle, the main anti-tumor immune steps, such as step 1 (release of cancer cell antigens), step 4 (T cell recruiting, CD8 T cell recruiting, Macrophage recruiting, NK cell recruiting, Th1 cell recruiting) and step 7 (Killing of cancer cells), showed a significant positive correlation with EMT risk score (Figure 5A, left, Supplementary Table S9).