CD4 and type 1 diabetes mellitus: Importantly, the positive correlation between hsa_circ_0004564 and CD3+ cells was validated in children with T1D after adjustments for CDAbs (p = 0.029) (Figure 5A), while no correlations were observed between hsa_circ_0004564 and HbA1c, FCP, PCP, DID, types of islet autoantibodies, or other immune cell subsets (i.e., CD4+ T cells, CD8+ T cells, and NK cells) (Figures 5B–D).