Furthermore, in most cancers, FDX1 expression was significantly positively correlated with m6A-, m5C-, and m1A-related genes, such as YTHDF1, YTHDF2, TRMT10C, and NSUN6. These findings suggest that the changes in the epigenetic status of FDX1 may contribute to tumorigenesis. The gene discussed is NSUN6; the disease is cancer.