FDX1 and cancer: Next, we evaluated the pathway through which FDX1 may be involved using GSEA in pan-cancer from TCGA and found that cytokine-cytokine receptor interaction and olfactory transduction pathways were closely correlated with FDX1 expression in most tumors, which was significantly positively correlated with BRCA, PCPG, and SARC (Figures 11H, O, R).