RASSF1 and gastric cancer: In addition, through microarray experiments, ursolic acid, which exists in the whole grass of Prunella vulgaris L., the leaves of Ilex rotunda Thunb, and many other botanical drugs, was found to exhibit inhibitory effects on the metastasis and proliferation of gastric cancer cells by modulating the Hippo pathway via the tumor suppressor gene Rassf1 (Kim et al., 2019).