ACKR3 and colorectal carcinoma: To investigate whether YAP1 inhibitor hinders EMT process in CRC by regulation of miR-124-3p and miR-188-5p in vivo, we performed RT-qPCR analysis and found that pharmacological inactivation of YAP1 with Verteporfin reversed the repression of miRNAs in AOM/DSS induced Villin-CXCR7 mice (Fig. 6D).