To further investigate whether nuclear YAP1 orchestrates the expression of Vimentin and DCLK1 by regulating miRNAs expression, we transfected CRC cells with a construct expressing the constitutive active form of YAP1 (YAP-5SA), resistant to LATS-mediated phosphorylation, which directly leads to YAP1 nuclear translocation. The gene discussed is YAP1; the disease is colorectal carcinoma.